中文簡介

《藥物靶向》雜志發表了關于藥物傳遞和分子和大分子藥物靶向的所有方面的論文和評論，包括為這些藥物的體外和/或體內應用設計和表征載體系統(膠體、蛋白質或聚合物)。論文不僅限于通過載體傳遞藥物，還包括針對特定細胞或細胞外分子的分子和大分子藥物的研究。因此，該雜志發表了包括基因/質粒DNA、基因沉默核酸(如小干擾RNA、反義寡核苷酸、核糖酶、DNAzymes)、適配體、單核苷酸和單克隆抗體及其偶聯物在內的治療肽/蛋白質和核酸的活性、傳遞和靶向性的研究結果。目標技術的診斷應用以及診斷和顯像劑的靶向交付也屬于該雜志的范圍。此外，還尋求關于自我調節系統、對環境和外部刺激作出反應的系統以及能夠產生程控、脈沖和其他復雜傳遞模式的系統的論文。藥物雜志的目標也有論文的生理和其他生物障礙交付和定位,和手段,克服障礙,例如,通過滲透增強劑,并涵蓋科目如溢出,在腫瘤擴散和目標組織,避免網狀內皮系統,和小說交付系統的毒性測試和許可。

　　英文簡介

The Journal of Drug Targeting publishes papers and reviews on all aspects of drug delivery and targeting for molecular and macromolecular drugs including the design and characterization of carrier systems (whether colloidal, protein or polymeric) for both vitro and/or in vivo applications of these drugs. Papers are not restricted to drugs delivered by way of a carrier, but also include studies on molecular and macromolecular drugs that are designed to target specific cellular or extra-cellular molecules. As such the journal publishes results on the activity, delivery and targeting of therapeutic peptides/proteins and nucleic acids including genes/plasmid DNA, gene silencing nucleic acids (e.g. small interfering (si)RNA, antisense oligonucleotides, ribozymes, DNAzymes), as well as aptamers, mononucleotides and monoclonal antibodies and their conjugates. The diagnostic application of targeting technologies as well as targeted delivery of diagnostic and imaging agents also fall within the scope of the journal. In addition, papers are sought on self-regulating systems, systems responsive to their environment and to external stimuli and those that can produce programmed, pulsed and otherwise complex delivery patterns. The Journal of Drug Targeting also carries papers on the physiological and other biological barriers to delivery and targeting, and means of overcoming the barriers, for example, by penetration enhancers, and covers subjects such as extravasation, diffusion in tumours and target tissues, avoidance of the reticulo-endothelial system, and toxicity testing and licensing of novel delivery systems.

　　近年期刊自引率趨勢圖

　　JCR分區

JCR分區等級	JCR所屬學科	分區	影響因子
Q2	PHARMACOLOGY & PHARMACY	Q2	5.016

　　近年期刊影響因子趨勢圖

　　CiteScore數值

CiteScore	SJR	SNIP	學科類別	分區	排名	百分位
8.80	0.793	0.847	大類：Pharmacology, Toxicology and Pharmaceutics 小類：Pharmaceutical Science	Q1	20 / 171	88%

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